Darlings of Durban follows the stories of four friends and how their lives intersect and influence each other.

Natasha owns a successful beauty company and is in a serious long-term relationship with the charming Sizwe. Natasha worries that his family will never truly accept her because of her mixed heritage. Does she even believe in marriage? Natasha often seeks the advice of her friend Sofia who's happily married with children. Sofia is the glue that holds the darlings together. The cousins, Farhana and Razia, both have their own complicated marriages. Farhana tries her best to support her husband in his harebrained schemes - even when it's to the detriment of her friendships. While Razia, the only darling in Johannesburg, feels stuck in her role as subservient wife to a husband whose attention is elsewhere.

All four women are navigating the complexities of love and life. But whatever life throws their way, the darlings always have each other.